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. Author manuscript; available in PMC: 2015 Sep 24.
Published in final edited form as: Org Biomol Chem. 2015 Sep 23;13(38):9793–9807. doi: 10.1039/c5ob01410g

Figure 2.

Figure 2

Top: a proposed double-fragmentation event in CID would lead to only two peptide-containing peaks in the MS2. Bottom: aryl disulfoxide linker cleaves only one bond at a time in a CID step, creating a four-peak pattern in MS2.