Table 1.

Dose proportionality of nitisinone PK parameters

	Estimate (beta)	95% CI lower	95% CI upper
AUC24 (μmol · h/L)	1.08	0.90	1.26
C max (μmol/L)	1.03	0.85	1.21

AUC ₂₄ area under the 24-hour serum concentration profile, CI confidence interval, C _max maximum serum concentration