Table 2.
Unadjusted and adjusted hazard ratios of virologic failure (n=6264) and treatment switching (n=6269)
| Univariate analysis | Multivariate analysis | ||||||
|---|---|---|---|---|---|---|---|
|
|
|
||||||
| cHR | 95% CI | p | aHR | 95% CI | p | PHA, VIF | |
| Virologic failure | 0.493, 1.01–1.16 | ||||||
| 6 months | 1 | 0.257 | 1 | 0.016 | |||
| 3 months | 1.10 | 0.93–1.29 | 0.78 | 0.64–0.95 | |||
| Treatment switchinga | 0.187, 1.01–1.23 | ||||||
| 6 months | 1 | 0.803 | 1 | 0.008 | |||
| 3 months | 1.02 | 0.85–1.23 | 0.73 | 0.58–0.92 | |||
cHR, crude hazard ratio; aHR, adjusted hazard ratio; PHA, p value for the global proportional-hazards assumption; VIF, range of variance inflation factors.
a
The variable age was categorized because the global proportional-hazards assumption was violated with age as a continuous variable (p= 0.039).