Table 4.
Brain tumors and psychotic symptoms[41]
| Ref. | Psychiatric symptoms | Tumor location | Tumor type | Remarks |
| Krayem et al[27], 2014 | Psychosis, auditory hallucinations, self-injurious behavior | Right temporal lobe | Astrocytoma | Psychosis developed either from tumor recurrence or right temporal brain tissue loss post-surgery |
| Kaloshi et al[80], 2013 | Visual and auditory hallucinations, spasmodic laughter, minimal spontaneous speech | Cerebellum | Glioneuronal | Partial improvement of symptoms with surgery |
| Arasappa et al[81], 2013 | Lethargy, anhedonia, persecutory delusions, and third person auditory hallucinations | Fourth ventricle | Choroid plexus papilloma | Improvement with surgery |
| Canuet et al[26], 2011 | Schizophrenia-like psychosis | Right parietal lobe | Meningioma | Psychosis developed 6 yr after initial surgery with tumor recurrence. Gradual improvement with antipsychotics |
| Bunevicius et al[46], 2008 | Schizophrenia | Left temporal lobe | Anaplastic oligodendroglioma | Improvement with surgery |
| Bunevicius et al[46], 2008 | Depression, psychosis | Left temporal lobe | Intra-cerebral cyst | Refractory symptoms |
| Bunevicius et al[46], 2008 | Schizophrenia | Left temporal lobe | Glioblastoma multiforme | |
| Parisis et al[82], 2003 | Peduncular hallucinosis (complex visual hallucinations), sleep impairment | Cerebellar metastases | Metastases | Mechanism thought to be extrinsic compression of posterior midbrain-pons by mass edema |
| Rueda-Lara et al[83], 2003 | Delusions, hallucinations | Pituitary | Hormone producing adenoma | |
| Maiuri et al[84], 2002 | Hallucinations | Posterior thalamus | Glioblastoma multiforme | Partial improvement of symptoms with surgical treatment and antidepressants |
| Miyazawa et al[85], 2001 | Headaches and psychotic symptoms | Pineal | Pineal meningioma | Improvement with surgery |
| Miyazawa et al[85], 2001 | Headaches and psychotic symptoms | Pituitary | Unknown | Improvement with steroid/hormone treatment |
| Craven[86], 2001 | Acute psychotic episode | Pineal | Germinoma | |
| Vardar et al[87], 2000 | Psychotic symptoms and cognitive deterioration | Right temporo-parietal | Arachnoid cyst | |
| Mordecai et al[88], 2000 | Psychotic and obsessive-compulsive symptoms, left-sided weakness, diabetes insipidus, decline in academic functioning | Bilateral basal ganglia | Germinoma | |
| Werring et al[89], 1999 | Visual hallucinations, palinopsia, posterior headache | Occipital | Tuberculoma | |
| Carson et al[90], 1997 | Pediatric psychosis - hallucinations, aggression, violence | Third ventricle | Choroid plexus papilloma | Symptoms improved after surgical removal |
| Ball[91], 1996 | Persecutory delusions, auditory and visual hallucinations, fluctuating levels of consciousness followed by grand-mal seizures | Cerebellopontine angle | Meningioma | |
| Filley et al[8], 1995 | Psychotic symptoms (perceptual disturbances) | Temporal | Low-grade oligoastrocytoma | |
| Okada et al[92], 1992 | Positive and negative psychotic symptoms | Left basal ganglia | Unknown | Positive symptoms resolved after surgical resection, but negative symptoms persisted |
| Trabert et al[93], 1990 | Symptoms of anorexia followed by seizures and psychosis | Temporo-basal | Angioma | |
| Nagaratnam et al[94], 1990 | Paranoid delusions | Left frontal lobe | Venous angioma | |
| Ko et al[57], 1989 | Paranoid ideation, irritability, short-term memory difficulties | Left parieto-occipital metastatic lesion | Origin in right kidney | No surgical intervention due to advanced stage |
| Dyck[95], 1985 | Auditory hallucinations | Sylvian fissure | Lipoma | |
| Binder[96], 1983 | Sudden behavioral changes followed by paranoid delusions; no focal neurologic signs | Right lateral ventricle | Meningioma | Complete resolution of symptoms after surgical intervention |
| Binder[96], 1983 | New-onset rage attacks on background of chronic schizophrenia | Bilateral occipital | Meningioma | Resolution of rage attacks after surgical removal |
| Dunn et al[97], 1983 | Peduncular hallucinations | Midbrain compression | Cystic craniopharyngioma | Prompt resolution after drainage of cyst |
| Soulairac et al[98], 1979 | Peduncular hallucinosis | Right temporal | Astrocytoma | |
| Buchanan et al[99], 1975 | Pressured speech, hypomania, persecutory delusions | Lateral ventricle | Meningioma | |
| Blustein et al[73], 1972 | Thought disorder, auditory hallucinations | Left parieto-occipital | Porencephalic cyst |
Adapted from Trends in Brain Cancer Research. New York: Nova Science Publishers Inc., 2006.