Table 2. MenJ Catalyzes the Final Step in Mycobacterial MK-9(II-H₂) Biosynthesis^a.

biosynthetic pathway	enzyme	M. tuberculosis gene	ref
chorismate
↓	MenF	Rv3215
isochorismate
↓	MenD	Rv0555
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate
↓	MenH	Rv2715
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate
↓	MenC	Rv0553
2-succinylbenzoic acid
↓	MenE	Rv0166	(37)
2-succinylbenzoyl-CoA
↓	MenB	Rv0548c	(34)
1,4-dihydroxy-2-naphthoate-CoA
↓	MenI	Rv1847
1,4-dihydroxy-2-naphthoate
↓	MenA	Rv0534c	(48)
demethylmenaquinone
↓	MenG	Rv0558, Rv0560c
menaquinone (MK-9)
↓	MenJ	Rv0561c	this study
saturated menaquinone [MK-9(II-H2)]

^aHomologues from mycobacteria that have been empirically identified are indicated with the appropriate reference. Putative homologues in Mycobacterium tuberculosis H37Rv genome are based on BLAST searches and annotations from online databases.