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The untreated control rat lung microvascular endothelial cells (RLMECs) transfected with TOPflash vector showed basal luciferase activity, which is expressed as 100%. Wnt3a treatment in RLMECs transfected with TOPflash vector showed significant increase in luciferase activity (*p<0.05). However, Wnt5a failed to show similar increase in luciferase activity.
