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. 2015 Sep 25;3:59. doi: 10.1186/s40478-015-0238-7

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© Atkinson et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Localization of C9ORF72 during development in vivo. a At P1, C9ORF72 (red) had punctate localization throughout the neuropil (arrows). b At P7, C9ORF72 labeling was present within nuclei (arrowheads) of neuronal cells (MAP2, green) and as strong puncta within cytoplasm and neuropil (arrows). c At P56, C9ORF72 labeling was present in the neuropil as puncta (arrows) and was localized to the cytoplasm surrounding nuclei (DAPI, arrowheads) Scale bar: 10 μm