Measured FRET intensity ratio for scaffold-adsorbed Fn, on oxidized (1.14 ± 0.23), neutral (1.09 ± 0.18), and reduced (1.05 ± 0.11) PEDOT:PSS scaffolds. Fn on oxidized scaffolds exhibits FRET ratios that are 10% higher than those observed on reduced scaffolds, indicating more compact Fn conformations in the oxidized state, and more unfolded Fn conformations in the reduced state (as illustrated by the schematics at bottom). In all cases, * indicates p < 0.05, and **** indicates p < 0.0001. Bars show means and standard deviations, with 8 to 20 measurements per condition.