Table 3a.
Effect of pubertal stage interaction on association of cardiometabolic risk score α by BMI
Cardiometabolic Risk Score α * | Boys (n = 828) | Girls (n = 1157) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
B | SE | P | R2 (95 % CI) | p (△F) | B | SE | p | R2 (95 % CI) | p (△F) | |
Model 1 | 35.0 % (29.7 % – 40.3 %) | <0.001# | 22.3 % (18.1 % – 26.6 %) | <0.001# | ||||||
ZBMI | 1.894 | 0.091 | <0.001 | 1.364 | 0.075 | <0.001 | ||||
Model 2 | 37.4 % (32.1 % – 42.7 %) | <0.001 | 26.1 % (21.7 % – 30.5 %) | <0.001 | ||||||
ZBMI | 2.019 | 0.092 | <0.001 | 1.722 | 0.088 | <0.001 | ||||
Pubertal stage: | ||||||||||
Pre-pubertal (ref) | ||||||||||
Pubertal | −0.594 | 0.235 | 0.012 | −0.460 | 0.240 | 0.055 | ||||
Late/Post-pubertal | −1.302 | 0.238 | <0.001 | −1.622 | 0.253 | <0.001 | ||||
Model 3 | 37.9 % (32.7 % – 43.1 %) | 0.024 | 26.8 % (22.4 % – 31.2 %) | 0.006 | ||||||
ZBMI | 1.747 | 0.164 | <0.001 | 2.485 | 0.255 | <0.001 | ||||
Pubertal stage: | ||||||||||
Pre-pubertal (ref) | ||||||||||
Pubertal | −0.477 | 0.239 | 0.046 | −1.260 | 0.346 | <0.001 | ||||
Late/Post-pubertal | −1.196 | 0.241 | <0.001 | −2.340 | 0.338 | <0.001 | ||||
Interaction terms: | ||||||||||
ZBMI * Pubertal | 0.593 | 0.224 | 0.008 | −0.903 | 0.302 | 0.003 | ||||
ZBMI * Late/Post-pubertal | 0.177 | 0.230 | 0.443 | −0.845 | 0.280 | 0.003 |
ZBMI : body mass index z score
B: un-standardized regression coefficient
SE: standard error
p: p-value testing the significance of the regression coefficient
R2: variance explained by the regression model
p (△F): p-value testing the significance of F change from the preceding model (# model 1 includes only the intercept term)
ref: reference group of the categorical variable that analyzed by creating dummy variables
*Cardiometabolic risk score α = Sum of components’ z score: Components of cardiometabolic risk score α include z-score of sex-specific, age-adjusted waist circumference, systolic and diastolic blood pressure (also height-adjusted), fasting plasma glucose, triglyceride and low-density lipoprotein cholesterol (LDL-C), and minus z-score of sex-specific age-adjusted high-density lipoprotein cholesterol (HDL-C)