Table 2.
Management of Systolic Blood Pressure (SBP) According to Age
| Variable | ≥75, n = 494 | <75, n = 2,526 | P-Value |
|---|---|---|---|
| Assigned SBP group, n (%) | |||
| Lower target (<130 mmHg) | 248 (50.2) | 1,253 (49.6) | |
| Higher target (130–140 mmHg) | 246 (49.8) | 1,273 (50.4) | |
| SBP at study entry, mean ± SD | 144.4 ± 20.0 | 142.7 ± 18.6 | .09 |
| SBP at end-study visit, mean ± SD | 130.3 ± 17.3 | 131.9 ± 16.9 | .07 |
| SBP at quarterly follow-ups, mean ± SDa | |||
| Lower target (<130 mmHg) | 125.2 ± 15.8 | 125.1 ± 14.4 | .64 |
| Higher target (130–140 mmHg) | 137.1 ± 14.6 | 137.1 ± 14.4 | .95 |
| Months to achieve SBP target, mean ± SD | 5.6 ± 6.1 | 5.9 ± 7.3 | .39 |
| Quarterly visits within assigned target, %, n (%) | |||
| ≤25 | 50 (10.4) | 226 (9.2) | .31 |
| >25–49 | 74 (15.4) | 354 (14.3) | |
| >50–74 | 168 (34.9) | 879 (35.6) | |
| ≥75 | 190 (39.4) | 1,009 (40.9) | |
| Antihypertensive medication adherence excellent or good at >75% of quarterly visits, n (%) | 423 (92.4) | 2,128 (91.4) | .50 |
| Always active in SBP treatment group, n (%) | 360 (72.9) | 1,913 (75.7) | .39 |
| Taking antihypertensive medications at study entry, n (%) | 433 (87.7) | 2,124 (84.1) | .04 |
| Number of antihypertensive medications, mean ± SD | |||
| Baseline | 1.6 (1.1) | 1.7 (1.2) | .19 |
| Year 1 visit | 2.0 (1.4) | 2.1 (1.4) | .17 |
| End-study visit | 1.9 (1.3) | 2.1 (1.5) | .003 |
| Years of follow-up, mean ± SD | 3.5 ± 1.9 | 3.7 ± 2.1 | .04 |
a
Excluding initial 6 months.
SD = standard deviation.