Table 2.

Association of previously described variants for CeD and T1D in the data set of double autoimmunity versus CeD-only patients

Chr	SNP	Position	A1	Allele freq.	OR (95% CI)	P	Reported disease	Risk allele	OR reported	P reported	Gene reported	Ref
3	rs17810546	161147744	G	0.16	0.72 (0.57, 0.92)	0.022	CeD	G	1.36	4 × 10−28	IL12A	19
10	rs1250552	80728033	G	0.44	1.24 (1.05, 1.46)	0.020	CeD	NR	1.12	9 × 10−10	ZMIZ1	19
2	rs3087243	204447164	G	0.58	1.41 (1.30, 1.55)	0.001	T1D+CeD	A	NR	8 × 10−11	CTLA4	20,22
12	rs17696736	110971201	G	0.47	1.22 (1.03, 1.45)	0.036	T1D+CeD	G	1.34	2 × 10−14	SH2B3/LNK/TRAFD1/PTPN11	20
1	rs2476601	114179091	A	0.12	2.16 (1.72, 2.72)	2.4 × 10−9	T1D	T	1.98	2 × 10−80	PTPN22	20
10	rs61839660	6134703	T	0.09	0.55 (0.39, 0.76)	0.001	T1D	NR	1.6	5 × 10−9	IL2RA	20
11	rs1004446	2126719	C	0.61	1.68 (1.58, 1.79)	1.2 × 10−7	T1D	C	1.61	4 × 10−9	INS	22
11	rs7111341	2169742	T	0.27	0.66 (0.54, 0.81)	4.6 × 10−4	T1D	NR	NR	4 × 10−48	INS	20
12	rs11171739	54756892	C	0.43	1.23 (1.04, 1.45)	0.026	T1D	C	1.34	1 × 10−11	ERBB3	33
16	rs12708716	11087374	A	0.64	1.24 (1.11, 1.39)	0.034	T1D	G/A	NR	7 × 10−13	CLEC16A/KIAA0350	22
16	rs4788084	28447349	G	0.57	1.21 (1.08, 1.37)	0.049	T1D	G	1.09	3 × 10−13	IL27	20

A1, allele associated; Allele freq., allele frequency for which OR is reported; Chr, chromosome; Gene reported, the most plausible gene reported by the literature; NR, not reported; Position, position in base pair; Ref, reference.