Table 3.

Association of previously described variants for CeD and T1D in the data set of double autoimmunity versus patients with T1D only

Chr	SNP	Position	A1	Allele freq.	OR (95% CI)	P	Reported disease	Risk allele	OR reported	P reported	Gene reported	Ref
1	rs2816316	190803436	A	0.83	1.32 (1.15, 1.53)	0.03086	CeD	A	1.25	2 × 10−17	RGS1	19
2	rs4675374	204510823	A	0.23	1.33 (1.08, 1.64)	0.00728	CeD	A	1.14	6 × 10−9	CTLA4/ICOS/CD28	19
3	rs11712165	120601486	C	0.38	1.22 (1.01, 1.46)	0.03101	CeD	C	1.13	8 × 10−9	CD80/KTELC1	19
3	rs1464510	189595248	A	0.46	1.28 (1.07, 1.54)	0.006945	CeD	A	1.29	3 × 10−40	LPP	19
2	rs3087243	204447164	G	0.61	1.36 (1.23, 1.51)	0.00126	T1D+CeD	G	1.15	8 × 10−11	CTLA4	20,22
10	rs12251307	6163501	T	0.09	1.46 (1.06, 2.0)	0.01756	T1D	T	NR	1 × 10−13	IL2RA	20

A1, allele associated; Allele freq., allele frequency for which OR is reported; Chr, chromosome; Gene reported, the most plausible gene reported by the literature; Position, position in base pair; Ref, reference.