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. 2015 Aug 24;146(2):281–291. doi: 10.1111/imm.12501

Figure 5.

Figure 5

Bronchoalveolar lavage (BAL) H-ficolin concentrations from infected lung transplant patients are higher than those found in non-infected patients. The BAL fluid was collected following bronchoscopies on lung transplant patients before the measurement of H-ficolin concentrations by ELISA. (a) The concentration of H-ficolin (ng/ml) in BAL samples. BAL samples were considered positive (n = 16) or negative (n = 16) for infection dependent upon patients classification according to EORTC/MSG criteria, Aspergillus antigen detection, radiology and bacterial, viral or fungal cultures. (b) H-Ficolin concentration in the BAL fluid of patients testing culture positive for Penicillium (Pen; n = 1), Pseudomonas aeuriginosa (PsA; n = 3), A. fumigatus (AsF; n = 4), Staphylococcus aureus (StA; n = 1), rhinovirus (Rhi; n = 1) or culture negative (Nil; n = 6). (c) Receiver operating characteristics curve analysis for H-ficolin detection in infected transplant patients compared with non-infected transplant patients. Results are representative of the data points gained from three independent experiments (16 positive and 16 negative patients). Bars represent the median and significance was determined via two-tailed Students t-test. *P < 0·05.