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. 2015 Sep 9;146(2):339–346. doi: 10.1111/imm.12512

Figure 3.

Figure 3

Il-17 deficiency affected numbers of CD8+ cells and myeloid-derived suppressor cells (MDSC) in spleen after streptozotocin (STZ) treatment. FACS analysis results of splenocytes after CD8 (a and c), Gr-1 and CD11b (b and d) staining. Single splenic cells were prepared from Il-17−/− and wild-type mice at various time-points after STZ or buffer injection. (e) Representative plots from FACS analysis of the splenic Gr-1+ CD11b+ cells with Ly6C, Ly6G and F4/80. Splenic cells were prepared from Il-17−/− and wild-type mice on Day 15 after STZ injections. Each group consisted of at least three individual mice. *P < 0·05.