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Overexpression of miR-367 in medulloblastoma cells enhances 3-D cell invasion. (a) Representative images of medulloblastoma spheroids displaying arboreal protrusions formed by cells invading the surrounding hydrogel matrix. Scale bar: 400 μm. (b) Kinetics of 3-D cell invasion of USP-13-Med spheroids overexpressing miR-367 (light grey line) and respective controls (miR-367 inhibitor and non-specific control). Significance level: ****P < 0.0001.
