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. 2015 Jul 14;106(9):1196–1201. doi: 10.1111/cas.12718

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© 2015 The Authors. Cancer Science published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Epstein–Barr virus (EBV) DNA load in nasopharyngeal (NP) brushing samples of non-nasopharyngeal carcinoma (NPC) control was significantly lower than that in stage I/II (a), T1/T2 (b), N0 (c) and M0 (d) diseases (P < 0.0001). Stage I/II (A) and T1/2 (b) disease also had a significantly lower level of EBV DNA load in NP brushing samples compared with advanced disease (P < 0.001). No significant difference was observed between node negative and positive cases (c) and between metastasis negative and positive cases (d).