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. 2015 Aug 20;106(9):1232–1239. doi: 10.1111/cas.12720

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© 2015 The Authors. Cancer Science published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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The correlation between the elastic modulus (EM) of cancer tissue and normal tissue, and TNM classification. (a) The EM of the cancer tissue is much higher than that seen for the normal tissue (P < 0.0001). (b) The EM of colorectal cancer was strongly correlated with T stage. The EM of T3 tumors was much higher than that seen in T2 (P < 0.0001). The EM of T4 was higher than that seen in T3 (P = 0.0055). (c) The EM of the tumors with lymph node metastasis was higher than that seen in tumors without lymph node metastasis (P = 0.0010). (d) The EM of the tumors with distant metastasis was higher than that seen in tumors without distant metastasis (P = 0.0111).