TABLE 3.
Expression of HNF4α target genes in the liver of C57BL/6J mice fed HFD or HFD + luteolin diets for 3 days
Results are mean ± S.E. (n = 5). *, p < 0.05; **, p < 0.01.
Gene | Relative mRNA expression (% of HF)a |
|
---|---|---|
HFD | HFD + 0.6% luteolin | |
% | % | |
HNF4α | 100 ± 11.0 | 64.9 ± 5.1* |
MTP | 100 ± 3.2 | 80.0 ± 5.7* |
ApoB | 100 ± 3.5 | 66.0 ± 6.9** |
HNF1α | 100 ± 8.0 | 70.8 ± 8.2* |
PEPCK | 100 ± 6.3 | 40.4 ± 17.0* |
G6Pase | 100 ± 10.8 | 49.4 ± 10.7* |
a The relative amount of each transcript was normalized to the amount of 36B4 transcript.