TABLE 6.
Expression of HNF4α target genes in the duodenum of C57BL/6J mice fed HFD or HFD + luteolin diets for 57 days
Results are mean ± S.E. (n = 8).
| Gene | Relative mRNA expression (% of HFD)a |
||
|---|---|---|---|
| HFD | HFD + 0.6% luteolin | HFD + 1.5% luteolin | |
| % | % | % | |
| HNF4α | 100 ± 17 | 117 ± 29 | 94.3 ± 24 |
| MTP | 100 ± 17 | 110 ± 26 | 97 ± 22 |
| ApoB | 100 ± 17 | 164 ± 41 | 100 ± 18 |
| HNF1α | 100 ± 20 | 127 ± 35 | 84.4 ± 36 |
| PEPCK | 100 ± 23 | 138 ± 35 | 132 ± 32 |
| G6Pase | 100 ± 15 | 103 ± 18 | 69 ± 13 |
a The relative amount of each transcript was normalized to the amount of 36B4 transcript.