TABLE 7.
Expression of HNF4α target genes in the jejunum of C57BL/6J mice fed HFD or HFD + luteolin diets for 57 days
Results are mean ± S.E. (n = 8).
| Gene | Relative mRNA expression (% of HFD)a |
||
|---|---|---|---|
| HFD | HFD + 0.6% luteolin | HFD + 1.5% luteolin | |
| % | % | % | |
| HNF4α | 100 ± 7.8 | 132 ± 19 | 137 ± 21 |
| MTP | 100 ± 8.4 | 187 ± 35 | 154 ± 29 |
| ApoB | 100 ± 9.4 | 148 ± 25 | 113 ± 24 |
| HNF1α | 100 ± 8.8 | 189 ± 32 | 190 ± 40 |
| PEPCK | 100 ± 24 | 155 ± 29 | 129 ± 25 |
| G6Pase | 100 ± 13 | 155 ± 39 | 69 ± 11 |
a The relative amount of each transcript was normalized to the amount of 36B4 transcript.