TABLE 8.
Expression of HNF4α target genes in the ileum of C57BL/6J mice fed HFD or HFD + luteolin diets for 57 days
Results are mean ± S.E. (n = 8). Values within a row without a common letter differ significantly (p < 0.05).
Gene | Relative mRNA expression (% of HFD)a |
||
---|---|---|---|
HFD | HFD + 0.6% luteolin | HFD + 1.5% luteolin | |
% | % | % | |
HNF4α | 100 ± 12 | 150 ± 24 | 116 ± 11 |
MTP | 100 ± 15 | 122 ± 21 | 98 ± 13 |
ApoB | 100 ± 15 | 113 ± 23 | 63 ± 7.7 |
HNF1α | 100 ± 11 | 125 ± 20 | 118 ± 28 |
PEPCK | 100 ± 38 | 74.4 ± 14 | 72.3 ± 15 |
G6Pase | 100 ± 11A | 120 ± 26A | 54.4 ± 4.2B |
a The relative amount of each transcript was normalized to the amount of 36B4 transcript.