TABLE 1.

Summary of A-CAT crystal structure features

A-CATa	PDB code	Name	Pep.b	Catalytic cleftc				Ref.
				Nucleotide	P-D766	Pi1	Mg2+
WT	3LMH	A-CAT·ADP·P	P1	ADP	+	−	−	19
WT	3LKM	A-CAT·AMP		AMP	−	+	Mg1,2	19
WT	3LLA	A-CAT-AMPPCP		AMPPCP	−	−	−	19
D766A	3LMI	A-CAT-D766A		ATP	−	−	Mg1	19
Δ809	3PDT	A-CAT-Δ809		ADP	−	−	Mg2	36
WT	4ZME	A-CAT·ADN·P	MH1	Adenosine	+	+	−	TWd
WT	4ZMF	A-CAT·AMP·P	P1	AMP	+	−	−	TW

^a Construct was crystallized; Δ809 indicates truncated at residue 809.

^b Pep. indicates peptide included in crystallization buffer as follows: P1, AAYKTKKKK; MH1, RKKFGESEKTKTKEFL.

^c Nucl. indicates identity of bound nucleotide; P-D766 indicates presence (+) or absence (−) of phosphorylated Asp-766; Pi1 indicates presence (+) or absence (−) of Pi bound to P-loop.

^d TW indicates this work.