FIGURE 2.

Lipin1 deficiency leads to impaired myogenic differentiation and reduced cyclin D·CDK4/CDK6 complex expression during regenerative myogenesis. A, the expression of myogenic factors and cell cycle regulators was detected by Western blot at days 0, 3, 5, and 7 after injury in TA muscle of fld and WT mice. B, protein expression levels of fld TA muscles at day 3 in response to muscle injury were quantified by densitometry and expressed as -fold change of WT controls. Data are representative of three independent experiments.*, p < 0.05; **, p < 0.01.