TABLE 2.

Functional classification of biological processes by GOEAST [PMID: 18487275]

GO Identification	Term	Level	Log Odds-Ratio	P
GO:0019752	Carboxylic acid metabolic process	6	2.26	2.27E-07
GO:0032787	Monocarboxylic acid metabolic process	7	2.64	5.72E-06
GO:0006631	Fatty acid metabolic process	8	2.79	4.40E-05
GO:0019217	Regulation of fatty acid metabolic process	6	3.75	0.002402
GO:0046470	Phosphatidylcholine metabolic process	8	4.46	0.01085
GO:0009062	Fatty acid catabolic process	9	3.78	0.010955
GO:0042304	Regulation of fatty acid biosynthetic process	7	4.29	0.015209
GO:0006695	Cholesterol biosynthetic process	7	4.29	0.015209
GO:0045833	Negative regulation of lipid metabolic process	6	3.64	0.015215
GO:0008203	Cholesterol metabolic process	6	3.12	0.018173
GO:0072329	Monocarboxylic acid catabolic process	8	3.48	0.022193
GO:0006635	Fatty acid β-oxidation	10	4.00	0.027045
GO:0016126	Sterol biosynthetic process	6	4.00	0.027045
GO:0019318	Hexose metabolic process	6	2.69	0.027395
GO:0046395	Carboxylic acid catabolic process	7	2.68	0.02781
GO:0046890	Regulation of lipid biosynthetic process	6	2.96	0.029911
GO:0007169	Transmembrane receptor protein tyrosine kinase signaling pathway	7	2.23	0.031379
GO:0006656	Phosphatidylcholine biosynthetic process	9	4.82	0.032319
GO:0015908	Fatty acid transport	10	3.72	0.047506
GO:0043066	Negative regulation of apoptotic process	7	1.60	0.049827

Levels 6–10 are shown. The top 200 most differentially expressed genes were selected, and the mouse genome was chosen as background in the analysis. Results with adjusted P < 0.05 and Log odds-ratio >1 are listed in the order of P value. Log odds-ratio indicates the relative abundance of this GO term compared with a random situation. Log odds-ratio = 1 means that this GO term is twice as abundant in the listed genes in comparison with the random situation.