TABLE 1.

List of genes sequenced

Phenotype	Gene	MIM Number	Disease	Locus	Number of Exons
Low HDL-C	ABCA1	600046	Tangier disease	9q31.1	50
Low HDL-C	APOA1	107680	ApoA-I deficiency	11q23-q24	5
Low HDL-C	APOA2	107670	ApoA-II deficiency	1q23.3	4
Low HDL-C	LCAT	606967	Familial LCAT deficiency/fish eye disease	16q22.1	6
Low HDL-C	NPC1	607623	Niemann-Pick disease	18q11.2	27
Low HDL-C	PLTP	172425	—	20q13.12	17
High HDL-C	CETP	118470	—	16q21	17
High HDL-C	GALNT2	602274	—	1q41-q42	16
High HDL-C	LIPG	603684	—	18q21.1	11
High HDL-C	SCARB1	601040	—	12q24.31	13
High LDL-C	ABCG5	605459	Sitosterolemia	2p21	16
High LDL-C	ABCG8	605460	Sitosterolemia	2p21	13
High LDL-C/low LDL-C	APOB	107730	FH	2p24-p23	29
High LDL-C	LDLR	606945	FH	19p13.2	18
High LDL-C	LDLRAP1	605747	FH	1p36-p35	13
High LDL-C/low LDL-C	PCSK9	607786	FH	1p32.3	12
Low LDL-C	MTTP	157147	Abetalipoproteinemia	4q24	19
High TG	APOA5	606368	—	11q23	4
High TG	APOC2	608083	Chlyomicronemia	19q13.2	4
High TG	APOE	107741	Dysbetalipoproteinemia	19q13.2	4
High TG	GPIHBP1	612757	—	8q24.3	4
High TG	LMF1	611761	—	16p13.3	20
High TG	LPL	609708	Chlyomicronemia	8p22	10
Low TG/high HDL-C	APOC3	107720	—	11q23.3	4
High lipoprotein (a)	LPA	152200	—	6q26	40
Statin myopathy	SLCO1B1	604843	—	12p	15

The MIM number is from the Online Mendelian Inheritance in Man database. FH, familial hypercholesterolemia.