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. 2015 Sep 25;10(9):e0138872. doi: 10.1371/journal.pone.0138872

Fig 1. Normal weight-gain of beta2-integrin knock-in mice on a high fat diet.

Fig 1

(A) Weight gain by WT and KI mice on a HF diet. (B) Body mass curves of age-matched WT and KI mice fed on a HF diet, monitored over a period of 20 weeks from 8–10 weeks of age. (C) Mean food intake per day of HF-fed WT and KI mice (D) Percentage lean and fat mass determined by qMR imaging in HF-fed 7-month-old male WT and KI mice. (E) Fasting blood leptin levels after 20 weeks HF-feeding for WT and KI mice. (F) Weights of tissues from WT and KI mice at the end of the 20-week HF-feeding study. (G) Respiratory exchange ratio (RER) for WT and KI mice at 20 weeks of HF diet; denoting overall mean RER over the 48 hour period and during light and dark phases. (n = 8–11. The results are means ± S.E.M. * P < 0.05; ** P < 0.01.