Table 1.
PN threshold and PN threshold – LV threshold difference at 0.4ms between LV pacing configurations in 28 patients conveyed in voltage and delivered energy. Data expressed in mean ± SEM.
Tip→RV | Tip→Can | Tip→Ring | Ring→RV | Ring→Can | Ring→Tip | P value | |
---|---|---|---|---|---|---|---|
Voltage | |||||||
PN (Volts) | 5.2 ± 0.8 | 5.3 ± 0.8 | 5.8 ± 0.7 | 9.1 ± 1.1 | 10 ± 1.1 | 8.4 ± 0.9 | 0.033 |
PN–LV difference | 3 ± 1.2 | 2.8 ± 1.3 | 2.6 ± 1.2| | 7.2 ± 1.3 | 7.9 ± 1.2‡ | 5.2 ± 1.2 | 0.019 |
Delivered energy | |||||||
PN (mJ) | 30.9 ± 9 | 29.4 ± 9.1 | 19.9 ± 5.2| | 84.6 ± 19 | 85.6 ± 17‡ | 41.1 ± 9.4 | 0.001 |
PN–LV difference | 26.4 ± 11 | 23.5 ± 12 | 14.2 ± 7§,| | 80.8 ± 20‡ | 80.3 ± 18‡ | 35.4 ± 11 | 0.0003 |
Note: P value refers to an overall test (repeated measures ANOVA) between all configurations. Repeated measures ANOVA showed that there was a significant configuration effect. Statistical difference between individual configurations is depicted as follows:
Tip→Ring;
Ring→RVcoil;
Ring→Can. Ring→Can vs. Tip→Ring configurations were statistically different in PN threshold-LV threshold difference (voltage and delivered energy), whereas Ring→RVcoil vs. Tip→Ring were statistically different in energy but not in voltage PN threshold-LV threshold difference. Bonferroni correction failed to identify statistical difference in voltage at PN threshold between individual configurations. Voltage and energy of PN thresholds at 0.4ms were derived using Lapique’s formula. mA, miliamperes; mJ, miliJoules.