Table 2.
MABP | RBF | CBF | OMBF | IMBF | V | UNaV | |
---|---|---|---|---|---|---|---|
| |||||||
mmHg | ml/min | PU | PU | PU | μl/min | μmol/min | |
STD (n=6) | 104±2 | 7.5±0.7 | 585±41 | 201±28 | 173±20 | 4.4±1.0 | 0.13±0.01 |
HS (n=7) | 112±5 | 6.5±1.7 | 625±79 | 136±19 | 152±18 | 9.6±3.6* | 2.69±1.21* |
HS+AUCB (n=6) | 114±7 | 9.5±3.1 | 678±78 | 231±42† | 135±30 | 10.2±1.6 | 2.42±0.51 |
HS+ABT (n=6) | 95±4† | 8.9±1.5 | 574±50 | 177±34 | 124±20 | 8.6±2.7 | 1.55±0.71 |
STD, HS - untreated rats on standard or high-sodium diet; HS+AUCB, HS+ABT - rats on high-sodium diet treated with soluble epoxide hydrolase inhibitor (AUCB) or CYP-450 inhibitor 1-aminobenzotriazol (ABT). PU - perfusion units; Means ± SEM,
significantly different from untreated STD rats,
significantly different from untreated STD rats.