Table 3. Comparison of chemotherapy induced vomiting control in both the groups as PDA versus OD group [n(%)].
| Antiemetic response Jones et al10 | Acute phase (day 1) No. (%) | Delayed phase (day 2–5)* No. (%) | Overall Response (Day 1–5) No. (%) | |
|---|---|---|---|---|
| Complete response | No emetic episode | 26 (86.7%) versus | 25 (83.3%) versus | 25 (83.3%) versus |
| 18 (60%) | 16 (53.3%) | 16 (53.3%) | ||
| p = 0.01, significant | p = 0.01, significant | p = 0.01, significant | ||
| Major response | 1–2 emetic episodes | 4 (13.3%) versus | 5 (16.6%) versus | 4 (13.3%) versus |
| 9 (30%) | 8 (26.6%) | 6 (20%) | ||
| p = 0.12, NS** | p = 0.35, NS** | p = 0.49, NS | ||
| Minor response | 3–5 emetic episodes | 0 (0%) versus | 0 (0%) versus | 01 (3.33%) versus |
| 2 (6.6%) | 4 (13.3%) | 5 (16.7%) | ||
| p = 0.15, NS** | p = 0.03, significant | p = 0.08, NS** | ||
| No response | >5 emetic episodes | 0 (0%) versus 1 (3.3%) | 0 (0%) versus 2 (6.6%) | 0 (0%) versus 3 (10%) |
| p = 0.31, NS** | p = 0.15, NS** | p = 0.07, NS** |
*
Delayed response is graded depending upon the worst observation from day 2–5.
**
NS = Not significant