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. 2015 Sep 25;10(9):e0138650. doi: 10.1371/journal.pone.0138650

Table 1. Viruses of A/California/07/2009 vaccines, and A/PR/8/34 and wild type A/California/07/2009 viruses used for deep sequencing analysis.

Note: CBER: Center for Biologics Evaluation and Research at US Food and Drug Administration.

Sample code Reference and Derivation Number of passages on eggs
X-181 X-181 1
X-181-M1 X-181 9
X-181-M2 X-181 9
X181-M3 X-181 13
X-181-M4 X-181 10
X-179A X-179A 1
X-179A-M1 X-179A 10
X-179A-M2 X-179A 11
X-179A-M3 X-179A 12
X-179A-M4 X-179A 11
X-179A-M5 X-179A 13
121XP-M4 121XP 10
A/Ca/07/2009 A/California/07/2009 1
A/PR/8/34 (CBER) A/Puerto Rico/08/34 1
A/PR/8/34-1* A/Puerto Rico/08/34 14
A/PR/8/34-3* A/Puerto Rico/08/34 14

*: A/PR/8/34 virus stock was passaged 13 times in eggs, and the last passaged virus was passaged one time (passage 14) separately in 2 different eggs, the 2 harvested viruses are designated as A/PR/8/34-1 and A/PR/8/34-3.