Fig 4. (a) RT-PCR analysis of Slt2 and Hog1 gene in budding yeast after drug treatment (i:Untreated control, ii: drug treated) (b) The expression of Slt2 and Hog1 mRNA, expressed as the ratio of densitometric measurement of the sample to the corresponding internal control (β-actin) (i: Untreated control, ii: drug treated) (c) Docking studies of Rohitukine with human two different type of member of MAPK pathway. (i) p38 (Hog1 in S. cerevisiae) and (ii) ERK5 (Slt2 in S. cerevisiae).
