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. 2015 Sep 25;10(9):e0138416. doi: 10.1371/journal.pone.0138416

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© 2015 Nagel et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 2 — HL cell lines U-HO1 (A) and KM-H2 (B) were analyzed by genomic profiling and FISH. Loci for OTX1 (2p15) in U-HO1 and for OTX2 (14q22) in KM-H2 are duplicated as shown by copy number (left) and FISH analyses (right), demonstrating duplicated and enhanced signals, respectively (arrows). BAC-probes cover (458N10) and flank (177J7, 262M6, 10P7, 350M3) the analyzed genes and are indicated in their labelling fluor colors.