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. 2015 Sep 25;10(9):e0139088. doi: 10.1371/journal.pone.0139088

Table 2. Incidence of PA in subgroups.

Characteristics PA (n = 97) % P
    Age (years)
≤35 16 2.73 0.000*
36~45 18 3.47
46~55 28 6.64
≥56 35 7.09
    Women 27 2.51 0.000*
    Men 70 7.41
    Hypertension 9 9.28 0.338*
    Diabetes 2 2.06 1.000
History of pituitary operation 3 1.79 0.056*
Pathological staining
Null (non functional) 63 7.31 NA
Functional 34 2.93
PRL 7 1.41
GH 8 3.88
ACTH 1 2.33
TSH 2 7.41
FSH 10 5.49
LH 0 0
Others 4 3.4
Multiple staining 2 2.3
    Total patients
Macroadenoma 93 10.11 0.000*
Microadenoma 4 0.36
    Men
Macroadenoma 67 13.67 0.000*
Microadenoma 3 0.66
    Women
Macroadenoma 26 6.05 0.000*
Microadenoma 1 0.15

NA, not applicable; PRL, prolactin; GH, growth hormone; LH, luteinizing hormone; ACTH, adrenocorticotropic hormone; TSH, thyroid-stimulating hormone; FSH, follicle-stimulating hormone. PA, clinical pituitary apoplexy.

* Pearson's chi-squared test.