Table 1.

Demographics, caudal:rostral metabolite concentrations ratios, and Working Memory Indices for All Subjects (controls: 1 – 10, cases: 11 – 29) sorted by age (in years).

#	Age/sex	DD	Medication	NAA	Cr	mI	WMI
1	23/M		—	1.02	1.12	1.54	111
2	28/M		—	0.97	0.99	0.99	95
3	29/F		—	0.85	0.84	1.24	119
4	31/M		—	1.01	1.44	0.97	84
5	34/F		—	0.99	0.97	1.04	119
6	36/M		—	0.99	1.35	1.16	113
7	43/M		—	0.94	1.04	0.96	94
8	46/M		—	0.93	0.87	0.92	136
9	47/M		—	1.06	1.13	1.04	102
10	55/F		—	0.88	1.04	0.88	95
11	22/M	48	Clozapine	1.03	1.10	1.14	108
12	23/M	3	Risperidone	1.00	1.03	1.02	113
13	25/M	60	Clozapine, valproic acid	0.91	0.98	0.95	99
14	26/M	8	Ziprasidone	1.07	1.43	0.77	—
15	29/F	8	Aripiprazole, bupropion, fluphenazine	1.19	1.26	1.24	82
16	38/F	276	Clonazepam, fluphenazine	1.12	1.36	0.94	63
17	41/M	264	Fluphenazine	1.65	1.18	1.09	80
18	42/F	23	Ziprasidone, bupropion, eszopiclone	1.25	1.32	1.38	65
19	43/F	240	Aripiprazole, escitalopram, fluphenazine	1.00	1.06	0.99	78
20	44/M	26	Clozapine, valproic acid	1.10	1.17	1.79	—
21	44/M	312	Clozapine, valproic acid	1.41	1.36	0.68	69
22	44/F	324	Quetiapine	1.42	1.29	1.02	90
23	48/M	276	Quetiapine	0.86	0.72	0.88	95
24	51/F	420	Ziprasidone, lithium, gabapentin	1.16	1.10	1.08	73
25	51/F	35	None	0.79	0.75	0.53	104
26	52/M	32	Citalopram	1.19	1.07	1.06	97
27	53/M	31	Clozapine, gabapentin, venlafaxine	1.29	1.28	1.32	104
28	55/F	432	Aripiprazole, quetiapine, trazadone	1.18	1.14	1.26	88

Note: F=female, M=male, DD=Schizophrenia disease duration (in months, patients only), NAA, Cr, mI = caudal:rostral ratio of this metabolite, WMI=WAIS-III Working Memory index.