Table 3.

Brain activity during 2-back task

Peak region	BA	Coordinates (x,y,z)	Cluster size	t-scove	p-value
A. ELS group
R Medial frontal gyrus	8	−41, −29, 39	10433	2.68	<0.001
L Medial prefrontal cortex	10	2, −56, 12	961	−3.57	<0.001
R Superior parietal lobule	7	−35, 58, 50	671	4.74	<0.001
R Inferior parietal lobule	13	−47, 32, 21	606	−2.61	<0.001
LPCC	23	2, 47, 24	535	−4.11	<0.001
L Inferior frontal gyrus	47	47, −32, −4	520	−4.40	<0.001
B. Control group
R Medial frontal gyrus	10	−2, −56, 21	8542	−4.95	<0.001
R Declive (Cerebellum)		−2, 38, −40	925	3.18	<0.001
L Superior frontal gyrus	6	2, −5, 51	498	5.89	<0.001
L Middle temporal gyrus	39	47, 71, 24	424	−2.98	<0.001
L Superior parietal lobule	7	32, 65, 51	350	2.80	<0.001
R Insula/Inf. frontal gyrus	13	−32, −20, 9	325	3.74	<0.001
L Middle frontal gyrus	6	32, 8, 60	323	3.41	<0.001
R Superior parietal lobule	7	−35, 62, 48	194	2.25	0.015
L Culmen (Cerebellum)		35, 56, −19	188	4.06	0.020
L Insula	13	29, −20, 12	159	4.39	0.065
L Thalamus		8, 8, 18	153	2.98	0.085
C. Group comparison
R Inferior frontal gyrus	47	−44, −23, −4	387	2.54	<0.001
R Inferior parietal lobule	39	−44, 65, 42	313	2.91	<0.001
L Superior temporal gyrus/IPL	39	53, 62, 27	284	2.71	<0.001
L PCC/precuneus	7	11, 77, 45	153	2.86	0.080

Abbreviations: BA Brodmann area, p-value FWE-corrected p-value, L left, R right, IPL inferior parietal lobule, PCC posterior cingulate cortex. Peak voxel coordinates based in the atlas of Talairach and Tournoux