Table 1.

Baseline functional data of isolated hearts from WT and ApoE KO mice fed with western high fat diet (ApoE-HFD).

	WT		ApoE-HFD
	M	F	M	F
No. of animals	34	32	29	28
Age, weeks	22 ± 0.3	22 ± 0.2	22 ± 0.4	22 ± 0.1
Body weight, g	27 ± 0.3	23 ± 0.3*	31 ± 0.3*	26 ± 0.2#&
Heart weight, mg	128 ± 2.3	97 ± 2.6*	150 ± 5.4*	112 ± 3.4*#&
Heart-to-body weight ratio, %	0.47 ± 0.01	0.42 ± 0.01*	0.48 ± 0.02	0.43 ± 0.01*#
Coronary flow, ml/min/g	15.8 ± 0.40	15.0 ± 0.52	16.0 ± 0.43	16.2 ± 0.55
LVDP, mmHg	106 ± 4.2	105 ± 3.0	110 ± 4.5	101 ± 3.6
Positive dP/dt, mmHg/s	4875 ± 368	4132 ± 446	4901 ± 521	4151 ± 507
Negative dP/dt, mmHg/s	4553 ± 342	3803 ± 532	4066 ± 321	3945 ± 226

^*p<0.05 vs. WT male,

^#p<0.05 vs. ApoE-HFD male,

^&p<0.05 vs. WT female