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. 2015 Sep 25;10(9):e0135288. doi: 10.1371/journal.pone.0135288

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Fig 1 — (A) Transmission electron micrographs of chitosan, Lipofectamine and CNs complexed with pEGFP. (B) Distribution and quantification of in vivo transfection of pEGFP in BAL cells of C57/BL6 mice. pG: Naked EGFP plasmid; C+pG: chitosan-complexed pG; L+pG: Lipofectamine-complexed pG; CN+pG: chlipid-complexed pG. (C) Quantification of IL-6 in BAL following intranasal administration of nanoparticles. C: chitosan; L: Lipofectamine; CN: chlipid; C+pV: chitosan-complexed pVAX DNA; L+pV: Lipofectamine-complexed pVAX DNA; and CN+pV: chlipid-complexed pVAX DNA.