Table 3. Gene ontology analysis.
| Gene Count | % of upregulated genes | P-value | Fold Enrichment | FDR | |
|---|---|---|---|---|---|
| Upregulated | |||||
| Ribosomal Protein | 38 | 11.95 | 3.6E-30 | 12.86 | 4.65E-27 |
| RNA Processing | 31 | 9.75 | 3.29E-10 | 3.9 | 5.19E-07 |
| Chromosomal Protein | 19 | 8.5 | 1.19E-11 | 8.37 | 1.53E-08 |
| Mitochondrial Protein | 42 | 13.2 | 9.3E-11 | 3.18 | 1.2E-07 |
| DNA Replication | 18 | 5.66 | 2.16E-09 | 6.51 | 3.41E-06 |
| Ribosome Biogenesis | 14 | 4.4 | 1.13E-07 | 6.87 | 1.79E-04 |
| Pyrimidine Metabolism | 16 | 5.03 | 1.5E-09 | 7.59 | 1.55E-06 |
| Downregulated | |||||
| GTPase Regulator | 58 | 6.98 | 1.19E-16 | 3.49 | 1.67E-13 |
| Cell Adhesion | 61 | 7.34 | 8.6E-10 | 2.35 | 1.52E-06 |
| Actin Cytoskeleton | 32 | 3.85 | 7.04E-10 | 3.66 | 9.73E-07 |
| Chromosome Organization | 44 | 5.29 | 2.7E-07 | 2.36 | 4.76E-04 |
| Embryonic Development | 48 | 5.77 | 1.7E-08 | 2.47 | 2.99E-05 |
| Transcription Regulation | 158 | 19.01 | 8.99E-09 | 1.53 | 1.59E-05 |
| Urogenital Development | 27 | 3.25 | 2.6E-09 | 4 | 4.59E-06 |
| Cell Motion | 44 | 5.29 | 1.73E-08 | 2.59 | 3.05E-05 |
| Extracellular Matrix | 39 | 4.7 | 3.69E-09 | 2.96 | 5.09E-06 |
| Pathways in Cancer | 42 | 5.05 | 5.53E-10 | 2.9 | 6.27E-07 |
| Zinc Finger | 93 | 11.2 | 4.9E-08 | 1.79 | 6.79E-05 |
The web based application Database for Annotation, Visualization and Integrated Discovery (DAVID) was used to sort lists of upregulated or downregulated genes by common function and enrichment using the Mus musculus background. A false discovery threshold of 1E-03 was used.