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. 2015 Sep 25;10(9):e0139210. doi: 10.1371/journal.pone.0139210

Table 1. Overview of the performance of the undiagnosed diabetes risk prediction models across the five imputation methods before (original) and after intercept adjustment (adjusted).

Models Performance measure Deletion Simple Conditional Stochastic Multiple
Original Adjusted Original Adjusted Original Adjusted Original Adjusted Original Adjusted
Cambridge diabetes risk model
E/O (95% CI) 1.81 (1.09; 2.52) 1.22 (0.61; 1.83) 2.07 (1.40; 2.75) 1.28 (0.69–1.87) 2.01 (1.28; 2.75) 1.27 (0.64–1.90) 2.17 (1.41; 2.93) 1.27 (0.64–1.90) 2.16 (1.40; 2.92) 1.30 (0.66–1.94)
Brier score 0.193 0.181 0.185 0.186 0.189
Yates slope 0.379 -1.401 -1.374 -1.399 -1.441
C-statistic (95% CI) 0.67 (0.62–0.72) 0.69 (0.65–0.73) 0.68 (0.63–0.72) 0.68 (0.64–0.73) 0.68 (0.64–0.72)
Kuwaiti Risk model
E/O (95% CI) 0.72 (0.40; 1.12) 0.94 (0.47–1.41) 0.79 (0.44; 1.14) 0.96(0.51–1.41) 0.79 (0.39; 1.20) 0.96 (0.45–1.47) 0.82 (0.44; 1.20) 0.96 (0.45–1.47) 0.82 (0.42; 1.22) 0.96 (0.55; 1.37)
Brier score 0.141 0.122 0.126 0.125 0.123
Yates slope 0.496 -0.459 -0.514 -0.473 -0.534
C-statistic (95% CI) 0.68 (0.63–0.73) 0.70 (0.66–0.74) 0.69 (0.65–0.73) 0.69 (0.65–0.74) 0.69 (0.65–0.73)
Omani diabetes risk model
E/O (95% CI) 1.28 (0.63; 1.93) 1.06 (0.47; 1.66) 1.40 (0.82; 1.98) 1.08 (0.56; 1.60) 1.40 (0.75; 2.05) 1.08 (0.50; 1.66) 1.56 (0.81; 2.30) 1.08 (0.50; 1.66) 1.54 (0.77; 2.31) 1.11 (0.51; 1.71)
Brier score 0.164 0.141 0.149 0.142 0.153
Yates slope 0.392 -1.065 -1.104 -1.049 -1.196
C-statistic (95% CI) 0.66 (0.61–0.70) 0.67 (0.63–0.71) 0.65 (0.61–0.70) 0.67 (0.63–0.72) 0.65 (0.61–0.69)
Rotterdam diabetes risk model
E/O (95% CI) 0.54 (0.50; 1.04) 0.98 (0.91–1.05) 0.65 (0.56; 0.74) 0.99 (0.83–1.14) 0.59 (0.48; 0.71) 0.99 (0.93–1.04) 0.65 (0.57; 0.74) 0.99 (0.93–1.04) 0.65 (0.57; 0.73) 0.99 (0.87–1.11)
Brier score 0.147 0.126 0.130 0.129 0.127
Yates slope 0.971 0.558 0.539 0.535 0.498
C-statistic (95% CI) 0.64 (0.59–0.69) 0.65 (0.61–0.70) 0.65 (0.60–0.69) 0.65 (0.60–0.70) 0.65 (0.61–0.70)
Simplified Finnish diabetes risk model
E/O (95% CI) 0.26 (0.13; 0.39) 0.89 (0.51; 1.26) 0.34 (0.17; 0.52) 0.92 (0.53; 1.31) 0.34 (0.18; 0.50) 0.92 (0.56; 1.28) 0.35 (0.17; 0.52) 0.92 (0.56; 1.28) 0.35 (0.17; 0.53) 0.92 (0.53;– 1.32)
Brier score 0.157 0.133 0.136 0.136 0.133
Yates slope 0.491 -0.021 0.080 -0.053 -0.045
C-statistic (95% CI) 0.67 (0.62–0.71) 0.66 (0.62–0.70) 0.67 (0.63–0.72) 0.66 (0.62–0.70) 0.66 (0.62–0.70)