Table 1. Overview of the performance of the undiagnosed diabetes risk prediction models across the five imputation methods before (original) and after intercept adjustment (adjusted).
Models | Performance measure | Deletion | Simple | Conditional | Stochastic | Multiple | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
Original | Adjusted | Original | Adjusted | Original | Adjusted | Original | Adjusted | Original | Adjusted | ||
Cambridge diabetes risk model | |||||||||||
E/O (95% CI) | 1.81 (1.09; 2.52) | 1.22 (0.61; 1.83) | 2.07 (1.40; 2.75) | 1.28 (0.69–1.87) | 2.01 (1.28; 2.75) | 1.27 (0.64–1.90) | 2.17 (1.41; 2.93) | 1.27 (0.64–1.90) | 2.16 (1.40; 2.92) | 1.30 (0.66–1.94) | |
Brier score | 0.193 | 0.181 | 0.185 | 0.186 | 0.189 | ||||||
Yates slope | 0.379 | -1.401 | -1.374 | -1.399 | -1.441 | ||||||
C-statistic (95% CI) | 0.67 (0.62–0.72) | 0.69 (0.65–0.73) | 0.68 (0.63–0.72) | 0.68 (0.64–0.73) | 0.68 (0.64–0.72) | ||||||
Kuwaiti Risk model | |||||||||||
E/O (95% CI) | 0.72 (0.40; 1.12) | 0.94 (0.47–1.41) | 0.79 (0.44; 1.14) | 0.96(0.51–1.41) | 0.79 (0.39; 1.20) | 0.96 (0.45–1.47) | 0.82 (0.44; 1.20) | 0.96 (0.45–1.47) | 0.82 (0.42; 1.22) | 0.96 (0.55; 1.37) | |
Brier score | 0.141 | 0.122 | 0.126 | 0.125 | 0.123 | ||||||
Yates slope | 0.496 | -0.459 | -0.514 | -0.473 | -0.534 | ||||||
C-statistic (95% CI) | 0.68 (0.63–0.73) | 0.70 (0.66–0.74) | 0.69 (0.65–0.73) | 0.69 (0.65–0.74) | 0.69 (0.65–0.73) | ||||||
Omani diabetes risk model | |||||||||||
E/O (95% CI) | 1.28 (0.63; 1.93) | 1.06 (0.47; 1.66) | 1.40 (0.82; 1.98) | 1.08 (0.56; 1.60) | 1.40 (0.75; 2.05) | 1.08 (0.50; 1.66) | 1.56 (0.81; 2.30) | 1.08 (0.50; 1.66) | 1.54 (0.77; 2.31) | 1.11 (0.51; 1.71) | |
Brier score | 0.164 | 0.141 | 0.149 | 0.142 | 0.153 | ||||||
Yates slope | 0.392 | -1.065 | -1.104 | -1.049 | -1.196 | ||||||
C-statistic (95% CI) | 0.66 (0.61–0.70) | 0.67 (0.63–0.71) | 0.65 (0.61–0.70) | 0.67 (0.63–0.72) | 0.65 (0.61–0.69) | ||||||
Rotterdam diabetes risk model | |||||||||||
E/O (95% CI) | 0.54 (0.50; 1.04) | 0.98 (0.91–1.05) | 0.65 (0.56; 0.74) | 0.99 (0.83–1.14) | 0.59 (0.48; 0.71) | 0.99 (0.93–1.04) | 0.65 (0.57; 0.74) | 0.99 (0.93–1.04) | 0.65 (0.57; 0.73) | 0.99 (0.87–1.11) | |
Brier score | 0.147 | 0.126 | 0.130 | 0.129 | 0.127 | ||||||
Yates slope | 0.971 | 0.558 | 0.539 | 0.535 | 0.498 | ||||||
C-statistic (95% CI) | 0.64 (0.59–0.69) | 0.65 (0.61–0.70) | 0.65 (0.60–0.69) | 0.65 (0.60–0.70) | 0.65 (0.61–0.70) | ||||||
Simplified Finnish diabetes risk model | |||||||||||
E/O (95% CI) | 0.26 (0.13; 0.39) | 0.89 (0.51; 1.26) | 0.34 (0.17; 0.52) | 0.92 (0.53; 1.31) | 0.34 (0.18; 0.50) | 0.92 (0.56; 1.28) | 0.35 (0.17; 0.52) | 0.92 (0.56; 1.28) | 0.35 (0.17; 0.53) | 0.92 (0.53;– 1.32) | |
Brier score | 0.157 | 0.133 | 0.136 | 0.136 | 0.133 | ||||||
Yates slope | 0.491 | -0.021 | 0.080 | -0.053 | -0.045 | ||||||
C-statistic (95% CI) | 0.67 (0.62–0.71) | 0.66 (0.62–0.70) | 0.67 (0.63–0.72) | 0.66 (0.62–0.70) | 0.66 (0.62–0.70) |