Table I.
Inhibition of thyroid cancer growth in vitro by trametinib and pazopanib.
| Cell line | Genotype | GI50
|
|
|---|---|---|---|
| Trametinib (nM) | Pazopanib (µM) | ||
| CAL62 | KRASG12R/G12R | 4.8±0.3 | 1.4±0.4 |
| BCPAP | BRAFV600E/wt | 4.0±1.7 | 3.2±0.5 |
| 8505C | BRAFV600E/V600E | 1.1±0.6 | 7.1±1.5 |
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