Figure 5.

Influences of SFRP2 on Wnt signaling pathway in lung cancer cells. (A) Representative images of β-catenin and phosphorylated β-catenin by western blotting in SFRP2-overexpressing A549 cells (right panel) and SFRP2-knockdowned 95-D cells (left panel). (B) Real-time RT-PCR detection of molecules related to Wnt signaling pathway in A549 and 95-D cells transfected for 48 h with SFRP2-overexpressing plasmid or SFRP2 siRNA, respectively. ov. and kn. represent overexpression and knockdown, respectively. Data are presented as mean ± SD. Statistical significance was evaluated using the Student's t-test. ^*P-value <0.05.