Table 1.

Kinetic isotope effects measured on five central metabolic enzymes. For multiply labeled isotopomers, α coefficients were approximated from KIEs of singly labeled isotopomers assuming KIEs are cumulative [28]; for instance, α ^PYR_110_PDH = α ^PYR_100_PDH. α ^PYR_010_PDH

Enzyme	Reaction	Substrate	Isotopomer	α	Ref.
6-phosphogluconate dehydrogenase	GND	PGN	100000	0.9905	[48]
glucose-6-phosphate dehydrogenase	G6PDH	G6P	100000	0.9837	[49]
fructose-1,6-bisphosphate aldolase	ALD	FBP	001000	0.9843	[50]
ribulose-5-phosphate epimerase	RPE	RB5P	01000	0.9931	[51]
			00100	0.9818
			00010	0.9852
			00001	0.9980
pyruvate dehydrogenase	PDH	PYR	100	0.9908	[52]
			010	0.9791
			001	0.9969