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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Allergy. 2015 Jul 24;70(10):1309–1318. doi: 10.1111/all.12683

Table 5.

eQTL of 7 of 24 other asthma genes (with significant eQTL)

SNP Gene Location Distance to Gene Chr Position Major Allele Minor Allele MAF TNIP1

BEC BAL

Beta* P-value (adjusted) Beta* P-value (adjusted)
rs10036748 TNIP1 intron −2295 5 150458146 C T 0.43 0.02 0.87 0.04 0.74
rs871269 TNIP1 intron −568 5 150432388 C T 0.38 0.10 0.49 −0.47 1.5x10−3 (0.03)

NOTCH4

rs404860 NOTCH4 intron −377 6 32184345 T C 0.2103 0.21 0.22 0.11 0.5518
rs2071279 NOTCH4 intron −25 6 32164874 G T 0.28 −0.13 0.37 −0.54 3.3x10−4 (0.05)

C11orf30

rs4300410 C11orf30 intron −150 11 76163151 C T 0.43 −0.08 0.52 −0.48 2.6x10−4 (0.01)
rs10793169 C11orf30 intron −346 11 76164012 G A 0.43 −0.08 0.52 −0.48 2.6x10−4 (0.01)
rs4245443 C11orf30 intron −40 11 76183924 G A 0.42 −0.09 0.51 −0.46 6.1x10−4 (0.02)
rs2508740 C11orf30 intron −4 11 76227182 A G 0.39 −0.04 0.75 −0.45 8.4x10−4 (0.03)
rs2513513 C11orf30 3UTR 342_1056 11 76261533 G A 0.42 −0.08 0.52 −0.44 1.0x10−3 (0.04)
rs2513525 C11orf30 3′ −4119 11 76266708 C A 0.42 −0.06 0.62 −0.43 9.1x10−4 (0.03)
rs7130588 C11orf30 3′ −8094 11 76270683 A G 0.32 −0.23 0.11 −0.26 0.09

SMAD3

rs4776890 SMAD3 intron −34347 15 67393045 T G 0.36 0.48 1.0x10−4 (5.3x10−3) −0.06 0.68
rs744910 SMAD3 intron −10448 15 67446785 G A 0.40 0.09 0.57 0.11 0.48

CDHR3

rs17152490 CDHR3 3′ −3361 7 105677579 G A 0.14 0.52 0.01 −0.08 0.69

ZBTB10

rs1543857 ZBTB10 5′ −103224 8 81295224 A G 0.48 −0.32 0.02 −0.12 0.41

DEXI

rs12919083 CLEC16A intron −25542 16 11188930 A C 0.37 0.18 0.28 0.63 1.0x10−4 (3.9x10−3)
*

Beta is the correlation coefficient of SNP vs. gene expression value on the basis of minor allele from linear additive model.