Figure 2.

Enrichment of CXCR3⁺ T cells in paraneoplastic neurologic disorder (PND) patient cerebrospinal fluid (CSF). (A) Flow cytometry analysis of PND patient cells showing CXCR3⁺CD4⁺ T cells (top panels) and CXCR3⁺CD8⁺ T cells (bottom panels) in CSF and peripheral blood. (B) Percentage of CD3⁺/CXCR3⁺ T cells in CSF and peripheral blood from individual PND patients. Percentage of CSF CD3⁺/CXCR3⁺ cells mean = 73; percentage of peripheral blood CD3⁺/CXCR3⁺ cells mean = 20.4. A t test assuming unequal variance was applied to the data with p < 0.05 considered significant. p = 2e10⁻⁸ for CSF versus peripheral blood CXCR3⁺ cells.