Table 3.
Relationships between EMT phenotype and clinicopathologic factors
| Factors | Total No. (%) | Complete No. (%) | Hybrid No. (%) | Null No. (%) | Wild No. (%) | p-value |
|---|---|---|---|---|---|---|
| Age (years) | ||||||
| ≤ 65 | 56 (57.7) | 5 (55.6) | 24 (57.1) | 10 (58.8) | 17 (58.6) | .998 |
| > 65 | 41 (42.3) | 4 (44.4) | 18 (42.9) | 7 (41.2) | 1 (41.4) | |
| Sex | . | |||||
| Male | 42 (43.3) | 7 (77.8) | 20 (47.6) | 9 (52.9) | 19 (65.5) | 256 |
| Female | 55 (56.7) | 2 (22.2) | 22 (52.4) | 8 (47.1) | 10 (34.5) | |
| Smoking | ||||||
| ≤ 10 PY | 59 (60.8) | 8 (88.9) | 24 (58.5) | 10 (58.8) | 17 (63) | .383 |
| > 10 PY | 37 (38.1) | 1 (11.1) | 17 (41.5) | 7 (41.2) | 10 (37) | |
| pT | ||||||
| 1 | 42 (43.3) | 3 (33.3) | 12 (28.6) | 8 (47.1) | 19 (65.5) | .148 |
| 2 | 41 (42.3) | 5 (55.6) | 23 (54.8) | 5 (29.4) | 8 (27.6) | |
| 3 | 9 (9.3) | 1 (11.1) | 5 (11.9) | 2 (11.8) | 1 (3.4) | |
| 4 | 5 (5.2) | 0 (0) | 2 (4.8) | 2 (11.8) | 1 (3.4) | |
| pN | ||||||
| 0 | 61 (62.9) | 7 (77.8) | 22 (59.5) | 13 (81.3) | 19 (70.4) | .649 |
| 1 | 8 (8.2) | 0 (0) | 6 (16.2) | 0 (0) | 2 (7.4) | |
| 2 | 19 (19.6) | 2 (22.2) | 8 (21.6) | 3 (18.8) | 6 (22.2) | |
| 3 | 1 (1.0) | 0 (0) | 1 (2.7) | 0 (0) | 0 (0) | |
| pM | ||||||
| 0 | 88 (90.7) | 9 (100) | 36 (85.7) | 17 (100) | 26 (89.7) | .267 |
| 1 | 9 (9.3) | 0 (0) | 6 (14.3) | 0 (0) | 3 (10.3) | |
| Stage | ||||||
| 1 | 54 (55.7) | 6 (66.7) | 18 (42.9) | 11 (64.7) | 19 (65.5) | .369 |
| 2 | 14 (14.4) | 1 (11.1) | 9 (21.4) | 1 (5.9) | 3 (10.3) | |
| 3 | 20 (20.6) | 2 (22.2) | 9 (21.4) | 5 (29.4) | 4 (13.8) | |
| 4 | 9 (9.3) | 0 (0) | 6 (14.3) | 0 (0) | 3 (10.3) | |
| Lymphovascular invasion | ||||||
| No | 39 (40.2) | 2 (22.2) | 16 (38.1) | 7 (41.2) | 14 (48.3) | .556 |
| Yes | 58 (59.8) | 7 (77.8) | 26 (61.9) | 10 (58.8) | 15 (51.7) | |
| Pleural invasion | ||||||
| No | 57 (58.8) | 4 (44.4) | 22 (52.4) | 8 (47.1) | 23 (79.3) | .058 |
| Yes | 40 (41.2) | 5 (55.6) | 20 (47.6) | 9 (52.9) | 6 (20.7) |
PY, pack years.