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Effect of ET induced by LPS pretreatment on liver function and levels of serum cytokine in ALF rats. The serum levels of alanine aminotransferase (ALT) (A), aspartate aminotransferase (AST) (B) and total bilirubin (TBiL) (C) were assayed using an automated blood chemistry analyzer. The serum concentrations of TNF-a, IL-6 and HMGB1 in ALF group (D) and ET+ALF group (E) were detected by ELISA assay and compared with that in control group (F).
