Table 2.
Univariate and Multivariate analysis of the effect of covariates on overall survival for all patients
| Factor | Univariate | Multivariate | ||
|---|---|---|---|---|
|
|
|
|||
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Sex | ||||
| Male | Reference | |||
| Female | 0.382 (0.229-1.761) | 0.634 | ― | ― |
| Age | ||||
| ≥60 | Reference | |||
| <60 | 1.658 (0.831-3.309) | 0.151 | ― | ― |
| Tumor size (cm) | ||||
| <5 | Reference | |||
| ≥5 | 0.914 (0.523-1.596) | 0.751 | ― | ― |
| Hepatitis | ||||
| Negative | Reference | |||
| HBV/HCV | 2.053 (1.090-8.553) | 0.054 | ― | ― |
| Live cirrhosis | ||||
| Absence | Reference | |||
| Presence | 0.777 (0.431-1.402) | 0.403 | ― | ― |
| TARBP1 expression | ||||
| Negative | Reference | Reference | ||
| Positive | 0.402 (0.217-0.744) | 0.004 | 2.773 (1.542-4.985) | 0.0019 |
| AJCC tumor stage | ||||
| I | Reference | Reference | ||
| II | 0.150 (0.036-0.631) | 0.010 | ― | |
| III | 0.393 (0.201-0.768) | 0.006 | 3.812 (1.579-9.423) | 0.004 |
| Clinical stage | ||||
| 1 | Reference | |||
| 2 | 0.301 (0.071-1.282) | 0.104 | ||
| 3 | 0.787 (0.450-1.376) | 0.401 | ― | ― |
HBV, hepatitis B virus; HCV, hepatitis C virus; AJCC, American Joint Committee on Cancer.