Figure 4.

MiR-451 inhibits GC cell migration and invasion in vitro. Over-expression of miR-451 significantly inhibited abilities of cell migration and invasion in miR-451-expressing stable BGC-823 cells compared with NC group. Data were expressed as the mean ± SD of at least three independent experiments (*P < 0.05). The migration and matrigel invasion assays showed that the number of migrated or invaded cells was significantly lower in the miR-451-overexpressed group than in the NC group (**P < 0.01).