Table 2.
Univariate and multivariate analyses of overall survival in patients
| Clinicopathological parameters | Comparison reference | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
|
|
|
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| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
| Tim-3 expression in CD4+T cells | Low/High | 0.153 (0.057-0.413) | <0.001 | 0.252 (0.073-0.871) | 0.029 |
| Tim-3 expression in CD8+T cells | Low/High | 0.094 (0.028-0.320) | <0.001 | 0.219 (0.050-0.950) | 0.043 |
| Gender | Female/Male | 0.957 (0.357-2.564) | 0.930 | 0.514 (0.149-1.767) | 0.291 |
| Age | <60/≥60 | 0.771 (0.330-1.803) | 0.548 | 1.680 (0.588-4.802) | 0.333 |
| Tumor size | <5 cm/≥5 cm | 0.389 (0.170-0.894) | 0.026 | 1.393 (0.514-3.777) | 0.515 |
| TNM stage | I, II/III, IV | 0.071 (0.017-0.306) | <0.001 | 0.092 (0.019-0.439) | 0.003 |