Figure 1.

Immunohistochemical demonstration of claudins protein and expression in human cervical carcinoma and adjacent tissue. Claudins and were expressed in the cell membrane. (A) High claudin-5 expression was detected in tissue adjacent to human cervical carcinoma compared with low expression in human cervical carcinoma tissue (B) (400×). (C) Claudin-7 was highly expressed in epithelial cells adjacent to cervical carcinoma and cancer tissue itself (D). (E) The low expression of claudin-8 in tissue adjacent to human cervical carcinoma compared to strong expression of claudin-8 in human cervical carcinoma tissue (F). (G) High claudin-9 expression was detected in tissue adjacent to human cervical carcinoma compared with low claudin-9 expression in human cervical carcinoma tissue (H) (400×).